Disease: PACHYONYCHIA CONGENITA 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TACSTD2 P09758 tumor associated calcium signal transducer 2 4.7E-03 0.537 0.731
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SLC12A9 Q9BXP2 solute carrier family 12 member 9 Transporter 1.2E-15 0.454 0.769
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MIR200B microRNA 200b 0.500 0.769
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885